Background: A pilot study was conducted to assess feasibility of using a mobile phone based system to send text messages and provide conditional cash transfers to improve vaccination timeliness. A grant is being submitted to fund a village-randomized control trial based off of successful pilot study. My research will answer several questions that are needed to conduct the RCT Immunizations are one of the most effective health interventions to reduce morbidity and mortality. In developing countries, DTP3 coverage is used as a surrogate to measure strength of immunization system. However, a high DTP3 coverage does not necessarily imply that children are being vaccinated in a timely fashion and in accordance with WHO schedules. Timeliness is important for two reasons; first, Hib and pertussis disease are often seen in early life and secondly, there are increased safety risks with delayed rotavirus immunization. Late vaccination reduces the maximum benefit vaccines afford.
Objectives & Methods: Assess individual and village coverage of DTP3 at 24 weeks of age in Gem, Kenya. Build a logistic regression model including socio-demographic indicators and distance from health facility to predict successful completion of DTP3. Analyze pilot study data and in combination with DTP3 coverage, perform sample size calculations and develop randomization allocation, stratified by geography and baseline DTP3 coverage.
Implications: This summer research project is needed to ensure a successful implementation of the 142 village randomized control trial that aims to improve vaccine coverage and timeliness. Results of regression model will be published and contribute to scientific literature.