Karen R. Charron
Instructor
Assistant Director of Academic Programs for GDEC
Departmental Address
615. N. Wolfe Street Room 5516
Baltimore, MD 21205
Research and Professional Experience
My research interests are primarily related to the conduct of clinical vaccine trials. I have served as co-investigator for numerous Phase I/II adult and pediatric vaccine trials of hepatitis B vaccines, preventive and therapeutic HIV vaccines, respiratory syncytial virus vaccines, rotavirus vaccines, dengue vaccines, and influenza virus vaccines.
My secondary area of interest is related to training of investigators and clinical teams for the clinical vaccine trial conduct, with a special emphasis on training investigators from developing countries. This includes applications of vaccine trials in accordance with the International Conference on Harmonisation (ICH) guidelines on the standards of Good Clinical Practice (GCP) and FDA and OHRP clinical trial regulations. Specific areas include: protocol development, partnerships in vaccines, human subjects protection, the informed consent process; data management; community education; recruitment; screening; investigational product management; protocol implementation, adverse event management, and standard operating procedures. This curriculum has evolved into the development of a distance education course entitled Clinical Vaccine Trials and Good Clinical Practice ntation which can be found at http://distance.jhsph.edu/vactrial.
This course is taught both 1st and 4th term of each academic year. I also develop and teach international regional workshops related to clinical vaccine trials.
I serve as the Assistant Director of Academic Programs for the Disease Prevention and Control Program coordinating the Masters of Health Sciences degree. I am always interested in speaking with potential students.
Keywords
International Health,
vaccine clinical trials,
informed consent, and
GCP
Honors and Awards
Alternate work address:
Center for Immunization Research
624 N. Broadway/ HH 217B
Baltimore, MD 21205
Selected Publications
Charron KR, Reynolds MJ. Outreaching to IVDU=s in the Hospital Setting. Community-Based AIDS Prevention: Studies of Intravenous Drug Users and Their Sexual Partners. Proceedings of the First Annual NADR National Meeting. NIDA Monograph: DHHS Publ. No. (ADM) 91-1752.
2. Harrison K, Vlahov D, Jones K, Charron KR, Clements ML. Medical Eligibility, Comprehension of the Consent process, and Retention of Injection Drug Users Recruited for an HIV Vaccine Trial. J Acq Immune Defic Syndr Hum Retrovir 10:386-90, 1995.
Online Clinical Vaccine Trials Course
