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Center for Global Health Faculty

Roberto Salvatori

Roberto Salvatori

Academic Degrees

Departmental Address

1830 East Monument St. #333

Contact Information

Phone:
410-955-3921
Fax:
410-955-8172
Link:
SciVal Experts Research Profile

Research and Professional Experience

Genetic of GH deficiency, role of GHRH in control of GH secretion

Keywords

growth hormone deficiency, genetics, atherosclerosis

Honors and Awards

1989: Italian Ministry of Education: fellowship for research abroad (nationwide competition). 1992: American Society for Clinical Investigation and American Federation for Clinical Research: Trainee Investigator Award for Excellence in Scientific Research. 1996: Outstanding Resident in Internal Medicine Award, Montefiore Medical Center, New York. 1998: The Endocrine Society Merck Senior Fellow Award. 1999: The Endocrine Society Travel Award

Selected Publications

1. Oliveira JL, Marques-Santos C, Barreto-Filho JA, Ximenes Filho R, Valadão de Oliveira Britto A, Oliveira Souza AH, Prado CM, Pereira Oliveira CR, Pereira RMC, de Almeida Ribeiro Vicente T, Teles Farias C, Aguiar-Oliveira MH and Salvatori R. Lack of Evidence of Premature Atherosclerosis in Untreated Severe Isolated Growth Hormone Deficiency Due to a GHRH Receptor Mutation. J Clin Endocrinol Metab. 2006 Mar 7; [Epub ahead of print] 2. Salvatori R, Serpa MG, Parmigiani G, Britto AVO, Oliveira JLM; Oliveira CRP; Prado CM, Farias CT, Almeida JC,. Vicente TA, and Aguiar-Oliveira MH. Growth hormone (GH) response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome. J Endocrinol Invest, 29: 122, 2006 3. Fintini D, Alba M, Schally AV, Bowers CY, Parlow AF, and Salvatori R. Effects of combined long-term treatment with a GHRH analog and GHRP-2 in the GHRH knock out mouse. Neuroendocrinology, 82: 198, 2006 4. Alba M, and Salvatori R. Naturally-occurring missense mutations in the human GHRH receptor alter ligand binding. J Endocrinol 186: 515-21, 2005. 5. Alcântara MRS, Salvatori R, Alcântara PRS, Nóbrega LMA, Campos VS, Oliveira ECO, Oliveira MHS, Oliveira Souza AH, and Aguiar-Oliveira MH Thyroid morphology and function in adults with untreated isolated growth hormone deficiency, J Clin Endocrinol Metab, 91: 860-4, 2006. 6. Fintini D, Salvatori R, Salemi S , Otten B, Ubertini G, Cambiaso P, and Mullis PE. Autosomal dominant isolated growth hormone deficiency (IGHD type II) with normal GH1 gene. Horm Res, 65:76-82, 2006 7. Haskin O, Lazar L, Jaber L, Salvatori R, Alba M, Kornreich L, Phillip M, and Gat-Yablonski G. A new mutation in the growth hormone-releasing hormone receptor gene in two Israeli Arab families. J Endocrinol Invest, 29: 122-130, 2006 8. Salvatori R. Adrenal Insufficiency JAMA 294: 2481-8, 2005. 9. Fintini D, Alba M, and Salvatori R. Influence of estrogen administration on the growth response to growth hormone (GH) in GH-deficient mice Exp Biol Med, 230: 715-20, 2005 10. Alba M, Fintini D, Bowers CY, Parlow AF, and Salvatori R.Effects of long term treatment with growth hormone releasing peptide-2 in the GHRH knock out mouse Am J Physiol Endocrinol Metab, 289: E762-7, 2005 11. Alba M, Schally AV, and Salvatori R. Partial reversibility of GH deficiency in the GHRH knock out mouse by postnatal treatment with a GHRH-analogue. Endocrinology 146:1506-13, 2005 12. Alba M, Fintini D, and Salvatori R Effects of recombinant mouse growth hormone treatment on growth and body composition in GHRH knock out mice. GH&IGF Res, 15:275-82, 2005 13. Alba M, and Salvatori R. A mouse with targeted ablation of the GHRH gene: a new model of isolated GH deficiency. Endocrinology 145: 4134-43, 2004 14. Alba M, Hall CM, Whatmore AJ, Clayton PE, David A. Price DA, and Salvatori R. Variability in anterior pituitary size within members of a family with GH deficiency due to a new splice mutation in the GHRH receptor gene. Clin Endocrinol (Oxf) 60: 470-5, 2004 15. Espigares R, Martin de Lara I, Ruiz-Cabello F, Ortega L, Ferrandez A, Argente J, and Salvatori R. Phenotypic analysis and growth response to different growth hormone treatment schedules in two siblings with an inactivating mutation in the growth hormone releasing hormone receptor gene. J Ped Endocrinol Metab 17: 793-800, 2004 16. Oliveira HA, Salvatori R, Krauss MPO, Oliveira CRP, Silva PRC, and Aguiar-Oliveira MH. Magnetic resonance imaging study of pituitary morphology in subjects homozygous and heterozygous for a null mutation of the growth hormone releasing hormone receptor gene. Eur J Endocrinol 148: 427-32, 2003 17. Carakushansky M, Whatmore AJ, Clayton PE, Shalet SN, Gleeson HK, Price DA, Levine MA, and Salvatori R. A new missense mutation in the growth hormone releasing hormone receptor gene in familial isolated GH deficiency. Eur J Endocrinol 148: 25-30, 2003 18. Salvatori R, Fan X, Veldhuis J, and Couch R. Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivating mutations in the GH-releasing hormone receptor gene. Eur J Endocrinol 147: 591-6, 2002 19. Salvatori R, Aguiar-Oliveira MH, Monte LVB, Hedges L, Santos NL, Pereira RMC, and Phillips III JA. Detection of a recurring mutation in the human GH-releasing hormone receptor gene. Clin Endocrinol (Oxf) 57: 77-80, 2002 20. Salvatori R, Fan X, Mullis PE, Haile A, and Levine MA. Decreased expression of the growth hormone-releasing hormone receptor gene due to a mutation in a Pit-1 binding site. Mol Endocrinol 16: 450-8, 2002

      
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