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Center for Global Health Faculty

Aaron Tobian

Aaron Tobian

Academic Degrees

Departmental Address

600 N. Wolfe St., Carnegie 437 Baltimore, MD, 21287

Contact Information

Keywords

Male circumcision, HIV, genital herpes (HSV-2), human papillomavirus (HPV), sexually transmitted infections, transfusion medicine, Uganda

Selected Publications

Selected Peer-Reviewed Publications from Last Two Years

1.    Tobian AAR, Serwadda D, Quinn TC, Kigozi G, Gravitt PE, Laeyendecker O, Charvat B, Ssempijja V, Riesdel M, Oliver AE, Nowak RG, Moulton LH, Chen MZ, Reynolds SJ, Wawer MJ, Gray RH.  Male circumcision for the prevention of HSV-2 and HPV infections and syphilis.  N Engl J Med 2009; 360:1298-309. 

2.    Redd AD, Dabitao D, Bream JH, Charvat B, Laeyendecker O, Kiwanuka N, Lutalo T, Kigozi G, Tobian AAR,  Gamiel J, Neal JD, Oliver AE, Margolick JB, Sewankambo N, Reynolds SJ, Gray RH, Wawer MJ, Serwadda D, and Quinn TC.  Microbial translocation, the innate inflammatory cytokine response, and HIV-1 disease progression in Africa.  PNAS 2009; 106: 6718-6723.  

3.    Johnson KE, Sherman ME, Ssempiija V,  Tobian AAR, Zenilman J, Duggan M, Redd AD, Kigozi G, Serwadda D, Chen M, Wawer M, Quinn TC, Rabkin CS, Gray RH.  Foreskin inflammation is associated with HIV and herpes simplex virus type 2 infections in Rakai, Uganda.  AIDS 2009; 23:  1807-1815.

4.  Tobian AAR, Ssempijja V, Kigozi G, Oliver AE, Serwadda D, Makumbi F, Nalugoda F, Iga B, Laeyendecker O, Chen MZ, Reynolds SJ, Wawer MJ, Quinn TC, and Gray RH.  Incident HIV and herpes simplex virus type 2 infection among men in Rakai, Uganda.  AIDS 2009; 23:  1589-1594.

5.  Tobian AAR, Gray RH, and Quinn TC.  Male circumcision prevents acquisition and transmission of sexually transmitted infections:  the case for neonatal circumcision.  Arch Pediatr Adolesc Med 2010; 164:  78-84.   

7.  Serwadda D, Gray RH, Tobian AAR, Chen MZ, Makumbi F, Suntoke T, Kigozi G, Nalugoda F, Iga B, Quinn TC, Moulton L, Laeyendecker O, Reynolds SJ, Kong X, Wawer MJ.  The role of genital ulcer disease and herpes simplex virus type 2 in the efficacy of male circumcision for HIV prevention.  PLoS Med 2009; 6: e1000187. 

6.   Johnson KE, Redd AD, Quinn TC, Collinson-Streng AN, Cornish T, Kong X, Sharma R, Tobian AAR, Tsai B, Sherman ME, Kigozi G, Serwadda D, Wawer M, Gray RH.  The effects of HIV-1 and HSV-2 infection on lymphocyte and dendritic cell density in adult foreskin tissue.  J Infect Dis.  2011; 203: 602-9.

7.   Wawer MJ*, Tobian AAR*, Kigozi G, Kong X, Gravitt PE, Serwadda D, Nalugoda F, Makumbi F, Ssempijja V, Sewankambo NK, Watya S, Eaton KP, Oliver AE, Chen MZ, Reynolds SJ, Quinn TC, Gray RH.  (*Tobian was corresponding author and joint first author).   Effect of circumcision of HIV-negative men on transmission of human papillomavirus to HIV-negative women: a randomised trial in Rakai, Uganda.  Lancet.  2011; 377:  209-218.

8.   Tobian AAR, Kong X, Wawer MJ, Kigozi G, Gravitt PE, Serwadda D, Eaton K, Nalugoda F, Quinn TC, Gray RH.  Circumcision of HIV-infected men and human papillomavirus transmission to female partners: analyses of data from a randomised trial in Rakai, Uganda.  Lancet Infectious Diseases.  2011; 11: 604-612.     

9.   Redd AD, Collinson-Streng A, Martens C, Ricklefs S, Mullis CE, Manucci J, Tobian AAR, Selig EJ, Laeyendecker O, Sewankambo N, Gray RH, Serwadda D, Wawer MJ, Porcella SF, and Quinn TC.  Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda using next generation deep sequencing.  J Clin Microbiol.  2011; 49: 2859-67.

10.  Tobian AAR and Gray RH.  The medical benefits of male circumcision.  JAMA.  2011; 306:  1479-1480.     

Projects

  • Information HIV and HSV-2 shedding and transmission in recently circumcised men.
  • Information Oncogenic HPV, Mucosal Immune Response and Risk of HIV Acquisition

      
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