MBBS , Patna Medical College
MPH , Johns Hopkins Bloomberg
I am a physician-scientist with a commitment to transdisciplinary research. My research aims to translate evidence into sound public policy and clinical care for patients by ensuring that stakeholders are well informed about treatment choices to make evidence based decisions. I have epidemiologic expertise in the conduct of rigorous systematic reviews, observational studies, multi-criteria decision analysis and benefit-risk assessment of drugs. My portfolio includes studies of medication safety. Representative work includes the detection of the risk of pancreatitis with GLP-based therapies for type 2 diabetes, risk of cardiovascular events with varenicline, inhaled anticholinergics and rosiglitazone. This work has been incorporated into national and international guidelines, and influenced policy in the US and abroad.
As Associate Director of the Methods Program at the Center for Public Health and Human Rights my international portfolio includes developing a new scale to measure human rights violations among men who have sex with men in Nepal. I also participate in multiple research projects including studies of sexual violence against women and a new scale to measure attack on health workers workers in conflict settings.
I teach courses in systematic reviews, evidence based medicine and human rights methods. As a general internist with an outpatient practice, I provides regular clinical care to patients
Honors and Awards
2013. Bruce Squires Award from the CMAJ for the Best Research Paper of the Year
2010, Society of General Internal Medicine Clinician-Investigator Award (Mid-Atlantic)
2009, Johns Hopkins Clinical Research Scholars NIH/NCRR Junior Faculty KL2 Award
2008, Delta Omega Alpha, Delta Omega Society, Johns Hopkins University
meta-researcher, comparative effectiveness and safety, drug safety, pharmacoepidemiology, evidence sythesis, meta-analysis, patient centered outcomes, health and human rights
Drug Safety/Comparative Effectiveness Research
Singh S, Loke YK. Drug Safety Assessment in Clinical Trials- Methodologic Challenges and Opportunities. Trials 2012 [ in press]
Moore T, Singh S, Furberg CD. The FDA and New Safety Warnings. Archives of Internal Medicine 2012 172:78-80
Singh S, Loke YK, Enright P, Furberg CD. The pro-arrhythmic and proischemic effects of inhaled anticholinergics. Thorax 2012
Singh S, Chang SM, Matchar DB, Bass EB. Grading a body of evidence on medical tests. AHRQ Publication No 12-EHC079-EF. Chapter 7 of the Methods Guide for Medical Test Reviews. 2012 ( AHRQ Publication No 12-EHC017). Rockville, MD : Agency for Health Care Research and Quality; June 2012; also published as a special supplement to the Journal of General Internal Medicine