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Center for Global Health Faculty

Zhiping Li

Director, transplant hepatology fellowship program

Academic Degrees

Departmental Address

760 Rutland Ave, Ross Bldg 918 Baltimore, MD 21205

Contact Information

Phone:
410-614-3530
Fax:
410-955-9677
Link:
SciVal Experts Research Profile

Research and Professional Experience

Dr. Li’s main clinical expertise is all aspects of liver disease, especially in area of Hepatitis B, primary sclerosing cholangitis (PSC) and bile duct diseases including bile duct cancer (cholangiocarcinoma). Dr Li also evaluates patients who need liver transplant and follow them post transplantation.

Dr. Li's main research focuses on pathogenesis of nonalcoholic fatty liver disease and associated insulin resistance. There are several areas of active investigation including the dietary modulation of the innate immune system of intestinal tract and liver, and their regulation on tissue injury and repair.

Selected Publications

Li Z, Lin HZ, Yang SQ and Diehl AM. Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system. Gastroenterology. 2002;123:1304-1310.

Li Z, Yang SQ, Lin HZ, Huang JW, Watkins PA, Moser AB, DeSimone C, Song XY, Diehl AM. Probiotics and antibodies to TNF inhibit inflammatory activity and improve non-alcoholic fatty liver disease. Hepatology. 2003;37: 343-350

Oben JA, Roskams T, Yang S, Lin H, Sinelli N, Li Z, Torbenson M, Huang J, Guarino P, Kafrouni M, and Diehl AM. (2003) Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. Hepatology. 2003;38. 664-673

Oben JA, Roskams T, Yang S, Lin H, Sinelli N, Torbenson M, Smedh U, Moran TH, Li Z, Huang J, Thomas SA, Diehl AM. Hepatic fibrogenesis requires sympathetic neurotransmitters. Gut. 2004;53:438-445.

Li Z, Oben JA, Yang S, Lin H, Stafford EA, Soloski MJ, Thomas S and Diehl AM. Norepinephrine regulates hepatic innate immune system in leptin deficient mice with nonalcoholic steatohepatitis. Hepatology. 2004;40:434-441

Li Z, Soloski MJ and Diehl AM. Dietary factors alter hepatic innate immune system in mice with non-alcoholic fatty liver disease. Hepatology. 2005;42:880-885.

Ma X, Hua J, Mohamood AR, Hamad AR, Ravi R and Li Z. A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. Hepatology. 2007;46:1519-1529

Maheshwari A, Maley W, Li Z, and Thuluvath PJ. Biliary complications and outcomes of liver transplantation from donors after cardiac death. Liver Transpl. 2007;13:1645-1653

Ma X, Torbenson M, Hamad AR, Soloski, MJ and Li Z. High-fat diet modulates non-CD1d restricted natural killer T cells and regulatory T cells in mouse colon and exacerbates experimental colitis. Clin Exp Immunol. 2008;151:130-138

Ma X, Hua J and Li Z. Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells. J Hepatol 2008;49:821-830

Projects

  • Information Collaboration with Renji Hospital in Shanghai, China

      
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