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Johns Hopkins is working on global health projects around the world. Use our search engine to explore our work in combating worldwide health threats.
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Projects
Cochrane Eyes and Vision Group
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The Cochrane Eyes and Vision Group aims to prepare, maintain and promote access to systematic reviews of interventions used to prevent or treat eye diseases and/or visual impairment. The work of the CEVG is carried out by over 300 members in more than 30 countries. The CEVG editorial team is located in London, UK and the CEVG US Project (CEVG@US) is a US-based satellite at the Johns Hopkins Bloomberg School of Public Health.
The CEVG@US is funded by the National Eye Institute. The overall objective of CEVG@US is to develop a critical mass of US-based vision researchers and practitioners who are trained in preparing and using systematic reviews.
The CEVG@US aims to accomplish four main goals: 1) Expand awareness of evidence-based health care in general and in eyes and vision specifically, 2) Develop a critical mass of vision researchers who are able to perform and interpret systematic reviews, and train others to do the same; 3) Develop a critical mass of clinicians who use the results of systematic reviews as an evidence base to guide their practice, and to train others to do the same; 4) Generate an increased number of systematic reviews in priority vision research areas, published in The...
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Projects
Mapping And Susceptibility Genes For Nonsyndromic Oral Clefts In Western China
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Oral clefts represent a major public health burden because of their high prevalence among newborns, the cost of surgical repair, and their continuing medical, psychological, and emotional burden to affected children and their families. While considerable progress has been made in recent years in identifying genes associated with isolated, nonsyndromic forms of oral clefts (including cleft lip or CL; cleft palate or CP; and cleft lip with palate or CLP), the genetic basis for this group of common malformations remains an enigma. It is clear that multiple genes influence risk to oral clefts and these genes likely interact with one another and with environmental risk factors. High throughput genotyping techniques are now available to permit genome wide tests of association and linkage in case-parent trio and case-control study designs. The Hopkins group has extensive experience in international collaborative research on oral clefts in China, and here we propose a collaborative study with colleagues at Western China University in Chengdu to support a case-parent trio study of 500 cleft probands, along with a sample of 500 control infants, that would involve genome wide tests for linkage and association to identify causal genes for oral clefts. This unique proposal combines the research...
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