Robert Gilman
Peru
Bloomberg School of Public Health, MS program
Risk of anemia among pregnant women in Peru is estimated to be 50 percent and may contribute to the high maternal mortality rate and 11 percent prevalence of low-birth weight neonates. To test our hypothesis that the risks and causes are not equally distributed across varying regions, we plan to assess the prevalence of anemia during pregnancy at a low altitude site in Lima, Peru (altitude of 268m) compared to that of a high altitude site of Puno, Peru (altitude of 3, 827m). Blood serum samples will be collected from 100 pregnant women attending health clinics at each site. Hemoglobin, hematocrit, serum transferrin, and serum folate measurements will be assessed from blood serum samples obtained from participants in their third trimester and postpartum. Additionally, the total iron binding capacity (TIBC) test, for which international organizations have requested validation studies, will be used. A follow-up assessment of the neonatal health will include acquisition of Apgar scores and birth weights for indication of associated birth outcomes. Fecal samples will be collected from participants to identify anemia related to hookworm, Necator americanus, infection, and avoid confounding within the study. A brief questionnaire will be administered to gather basis health information from each mother to assist in identifying risk factors, and estimate the current status of antenatal care and supplementation methods within the local health centers. Characterization of maternal anemia among varying populations is necessary to inform health service decisions as to the most appropriate anemia prevention and treatment programs. Additionally, comparison of test results, and validation of TIBC use will further complement the body of knowledge regarding the most accurate methods, and assist in standardization of maternal anemia measurements.
| 
